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wildtype vs wild-type

Both 'wildtype' and 'wild-type' are correct, but 'wild-type' is more commonly used in scientific contexts. The hyphenated form is preferred when referring to the standard, non-mutated form of a gene or organism.

Last updated: March 24, 2024 • 1508 views

wildtype

This is a correct term, but less common than 'wild-type'.

It refers to the standard, non-mutated form of a gene or organism. It is used in genetics and biology.

Show examples from the web [+]

The organism used has not been genetically engineered and has been derived from a single wildtype organism Alcaligenes eutrophus strain H16 NCIMB 10442.
These isolates expressed a median fold change in EC50 relative to wildtype of 12.0 for atazanavir.

Alternatives:

wild-type

wild-type

This is the more commonly used form, especially in scientific contexts.

It refers to the standard, non-mutated form of a gene or organism. It is used in genetics and biology.

Show examples from the web [+]

The safety profile of panitumumab in patients whose tumour express KRAS wild-type (n = 123) was generally consistent with overall mCRC monotherapy set described above.
Two percent of patients with KRAS wild-type had diarrhoea reported as severe.
(1) Reports have indicated that contracting of wild-type measles during pregnancy enhances foetal risk.
Viral resistance to abacavir develops relatively slowly in vitro, requiring multiple mutations for a clinically relevant increase in EC50 over wild-type virus.
1. Live salmonella vaccines shall not be used in the framework of national control programmes where the manufacturer does not provide an appropriate method to distinguish bacteriologically wild-type strains of salmonella from vaccine strains.
where the manufacturer does not provide an appropriate method to distinguish bacteriologically wild-type strains of Salmonella from vaccine strains.
The difference in median PFS in the KRAS wild-type group was 8 weeks.
Antiviral activity: entecavir inhibited HBV DNA synthesis (50% reduction, EC50) at a concentration of 0.004 µM in human HepG2 cells transfected with wild-type HBV.
Resistance in cell culture: relative to wild-type HBV, LVDr viruses containing rtM204V and rtL180M substitutions within the reverse transcriptase exhibit 8-fold decreased susceptibility to entecavir.
Stable disease rates in the KRAS wild-type group were 34% for panitumumab and 12% for BSC.
Further evidence is also awaited regarding the effect of panitumumab in combination with chemotherapy on PFS in patients with wild-type KRAS tumours.
Post-exposure vaccination Vaccination of individuals exposed to wild-type measles may provide some protection if the vaccine can be administered within 72 hours after exposure.
In the KRAS wild-type group the response rate was 17% for panitumumab and 0% for BSC.
This means that further evidence on this medicinal product is awaited, in particular data are required to confirm the effect in patients with wild-type KRAS tumours which is currently supported by a retrospective analysis.
Resistance in cell culture: relative to wild-type HBV, LVDr viruses containing rtM204V and rtL180M substitutions within the reverse transcriptase exhibit 8-fold decreased susceptibility to entecavir.
There have been reports of SSPE in children who did not have a history of infection with wild-type measles but did receive measles vaccine.
0.37-0.65) in favour of panitumumab in the KRAS wild-type group and 1.07 (95% CI:
14.0, 31.9) for those with KRAS wild-type tumours and 0% (95% CI:
The concentration of tenofovir required for 50% inhibition (EC50) of the wild-type laboratory strain HIV-1IIIB is 1-6 µmol/ l in lymphoid cell lines and 1.1 µmol/ l against primary HIV-1 subtype B isolates in PBMCs.
In circumstances where contact with high-risk individuals susceptible to varicella is unavoidable, the potential risk of transmission of the varicella vaccine virus should be weighed against the risk of acquiring and transmitting wild-type varicella virus.

Alternatives:

wildtype

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