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wild-type vs wild type

Both "wild-type" and "wild type" are correct, but "wild-type" is more commonly used in scientific contexts. The hyphenated form is preferred when used as an adjective to describe a specific type of organism or gene.

Last updated: March 24, 2024 • 846 views

wild-type

This is correct, especially in scientific contexts.

The term "wild-type" is commonly used in genetics and biology to refer to the standard, normal, or typical form of an organism or gene. It is usually hyphenated when used as an adjective.
  • The safety profile of panitumumab in patients whose tumour express KRAS wild-type (n = 123) was generally consistent with overall mCRC monotherapy set described above.
  • Two percent of patients with KRAS wild-type had diarrhoea reported as severe.
  • (1) Reports have indicated that contracting of wild-type measles during pregnancy enhances foetal risk.
  • Viral resistance to abacavir develops relatively slowly in vitro, requiring multiple mutations for a clinically relevant increase in EC50 over wild-type virus.
  • 1. Live salmonella vaccines shall not be used in the framework of national control programmes where the manufacturer does not provide an appropriate method to distinguish bacteriologically wild-type strains of salmonella from vaccine strains.
  • where the manufacturer does not provide an appropriate method to distinguish bacteriologically wild-type strains of Salmonella from vaccine strains.
  • The difference in median PFS in the KRAS wild-type group was 8 weeks.
  • Antiviral activity: entecavir inhibited HBV DNA synthesis (50% reduction, EC50) at a concentration of 0.004 µM in human HepG2 cells transfected with wild-type HBV.
  • Resistance in cell culture: relative to wild-type HBV, LVDr viruses containing rtM204V and rtL180M substitutions within the reverse transcriptase exhibit 8-fold decreased susceptibility to entecavir.
  • Stable disease rates in the KRAS wild-type group were 34% for panitumumab and 12% for BSC.
  • Further evidence is also awaited regarding the effect of panitumumab in combination with chemotherapy on PFS in patients with wild-type KRAS tumours.
  • Post-exposure vaccination Vaccination of individuals exposed to wild-type measles may provide some protection if the vaccine can be administered within 72 hours after exposure.
  • In the KRAS wild-type group the response rate was 17% for panitumumab and 0% for BSC.
  • This means that further evidence on this medicinal product is awaited, in particular data are required to confirm the effect in patients with wild-type KRAS tumours which is currently supported by a retrospective analysis.
  • Resistance in cell culture: relative to wild-type HBV, LVDr viruses containing rtM204V and rtL180M substitutions within the reverse transcriptase exhibit 8-fold decreased susceptibility to entecavir.
  • There have been reports of SSPE in children who did not have a history of infection with wild-type measles but did receive measles vaccine.
  • 0.37-0.65) in favour of panitumumab in the KRAS wild-type group and 1.07 (95% CI:
  • 14.0, 31.9) for those with KRAS wild-type tumours and 0% (95% CI:
  • The concentration of tenofovir required for 50% inhibition (EC50) of the wild-type laboratory strain HIV-1IIIB is 1-6 µmol/ l in lymphoid cell lines and 1.1 µmol/ l against primary HIV-1 subtype B isolates in PBMCs.
  • In circumstances where contact with high-risk individuals susceptible to varicella is unavoidable, the potential risk of transmission of the varicella vaccine virus should be weighed against the risk of acquiring and transmitting wild-type varicella virus.

Alternatives:

  • wild type

wild type

This is correct, but less common in scientific contexts.

While "wild type" without the hyphen is also acceptable, it is less common in scientific literature. It can still be used to refer to the standard form of an organism or gene.
  • The effectiveness of Nobivac Piro has been studied in three laboratory studies in which dogs were vaccinated and then challenged (exposed to wild type Babesia).
  • There must also be information as to whether or not the micro-organism is a wild type or a spontaneous or induced mutant, or a genetically modified organism.
  • The median fold IC50 of lopinavir for these 18 isolates at baseline and rebound was 6.9- and 63-fold, respectively, compared to wild type virus.
  • Isolates retained susceptibility to tipranavir with a median increase of IC50 in baseline and rebound isolates of 1.9- and 1.8- fold, respectively, compared to wild type virus.
  • if available and suitable, tests to distinguish the antibody pattern elicited by a marker vaccine from the one elicited by the wild type of classical swine fever virus,
  • "marker vaccine" means a vaccine that can elicit a protective immunity distinguishable from the immune response elicited by the natural infection with the wild type virus by means of laboratory tests carried out in accordance with the diagnostic manual;
  • Instability of the genetic modification may in certain cases result in reversion into the wild type phenotype.
  • Available information on the relationship with naturally occurring wild type relatives shall be taken into account.
  • You're the wild type, Sarah.
  • He said she was this wild type, you know, who had a lot of guys chasing her.
  • Recombinant viruses showing >= 3-fold resistance to tipranavir grow at less than 1% of the rate detected for wild type HIV-1 in the same conditions.
  • 62 humans; all showed activity that was at least 10-fold less than the activity of darunavir against wild type HIV.
  • Mutations at position 82 occur via two pathways: one from pre-existing mutation 82A selecting to 82T, the other from wild type 82V selecting to 82L.
  • No lymphomas were observed following 6 months treatment with an antibody analogue of efalizumab in a 6 months study with p53 +/ + wild type mice.
  • The median fold IC50 of lopinavir for these 18 isolates at baseline and rebound was 6.9- and 63-fold, respectively, compared to wild type virus.
  • Antiviral activity in vitro Etravirine exhibits activity against wild type HIV-1 in T-cell lines and primary cells with median EC50 values ranging from 0.9 to 5.5 nM.
  • At least 3 oxidative metabolites of darunavir have been identified in humans; all showed activity that was at least 10-fold less than the activity of darunavir against wild type HIV.
  • Although etravirine demonstrates in vitro activity against wild type HIV-2 with median EC50 values ranging from 5.7 to 7.2 µM, treatment of HIV-2 infection with etravirine is not recommended in the absence of clinical data.
  • Domestic geese and ducks have been selected for meat and egg production, but all breeds retain most of their 'wild type' behaviour and are generally more nervous and easily upset than other domestic birds, especially when they are moulting.
  • Genetically normal animals (wild type offspring) produced as a result of creation of a new genetically altered line should not be reported.

Alternatives:

  • wild-type

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