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virus resistance vs antiviral resistance

Both phrases are correct, but they are used in different contexts. 'Virus resistance' refers to the ability of an organism to withstand or repel a virus, while 'antiviral resistance' refers to the ability of a virus to withstand the effects of antiviral medications.

Last updated: March 30, 2024 • 720 views

virus resistance

This phrase is correct and commonly used in the context of an organism's ability to withstand or repel a virus.

This phrase is used to describe the ability of an organism to resist or defend against a virus, such as in the context of plant breeding for virus resistance.

Examples:

  • The new crop variety shows strong virus resistance.
  • Genetic modifications can enhance virus resistance in plants.
  • Doing so could increase the risk of the virus developing resistance.
  • This way, you can be sure your medicine is fully effective and you reduce the risk of the virus developing resistance to the treatment.
  • This may mean that the HIV virus will develop resistance to ISENTRESS and become harder to treat.
  • Threats such as pandemic influenza, malaria and tuberculosis are a health risk because of virus mutations, increasing resistance to antibiotics and weak health systems.
  • At time of failure with CXCR4-using virus, the resistance pattern to other antiretrovirals appears similar to that of the CCR5-tropic population at baseline, based on available data.
  • The virus is significant in its extraordinary resistance to environmental factors.
  • Background resistance to other classes of antiretrovirals have been shown to be similar in previously undetected CXCR4-tropic virus of the minor viral population, as that found in CCR5-tropic virus.
  • Resistance to entecavir (when a virus becomes insensitive to the antiviral) has been seen in lamivudine-refractory patients.
  • Resistance In vitro selection of darunavir-resistant virus from wild type HIV-1 was lengthy (> 3 years).
  • HBV strains expressing the adefovir-associated resistance mutations rtA181V and rtN236T showed a susceptibility to tenofovir ranging from 2.9- to 10-fold that of wild-type virus.
  • Viral resistance to abacavir develops relatively slowly in vitro, requiring multiple mutations for a clinically relevant increase in EC50 over wild-type virus.
  • The phenotypic resistance test performed required a minimum of 1000 copies/ ml HIV RNA in order to be able to amplify the virus.
  • In cell based assays, HBV strains expressing the rtV173L, rtL180M, and rtM204I/ V mutations associated with resistance to lamivudine and telbivudine showed a susceptibility to tenofovir ranging from 0.7- to 3.4-fold that of wild-type virus.
  • HBV strains expressing the rtL180M, rtT184G, rtS202G/ I, rtM204V and rtM250V mutations associated with resistance to entecavir showed a susceptibility to tenofovir ranging from 0.6- to 6.9-fold that of wild- type virus.
  • As the virus has the capability to develop resistance to antiretroviral agents, it is increasingly important to monitor the development of resistant strains. Insufficient laboratory capacity can be an obstacle to producing relevant susceptibility data.
  • 10 vitro studies indicate that zidovudine-resistant virus isolates can become zidovudine sensitive when they simultaneously acquire resistance to lamivudine.
  • Scientists fear that massive use of this will lead to considerable environmental pollution of the natural microflora and a significant build-up of resistance in the virus strains.
  • Phenotypic resistance: in patients with CCR5-tropic virus at time of treatment failure with CELSENTRI, 22 out of 58 patients had virus with reduced sensitivity to maraviroc.
  • Its extreme infectiousness and high degree of resistance, which vary according to the strain of the virus in question, call for the taking of draconian measures in infected areas.
  • Their genetic make-up was modified via the implantation of the Medusa gene, which means that they become fluorescent when in contact with blue light, and the Rhesus macaque gene which grants them resistance to the AIDS virus.

Alternatives:

  • immune response to viruses
  • virus immunity
  • virus tolerance
  • virus defense mechanisms
  • virus susceptibility

antiviral resistance

This phrase is correct and commonly used in the context of viruses developing resistance to antiviral medications.

This phrase is used to describe the ability of a virus to resist the effects of antiviral medications, leading to treatment challenges and the need for alternative therapies.

Examples:

  • The emergence of antiviral resistance is a major concern in the treatment of HIV.
  • Overuse of antibiotics can contribute to antiviral resistance.
  • Improve rational use of antibiotics and fighting antimicrobial and antiviral resistance [31] (Annex - points 1.2.3)
  • Antivirals and Antiviral Resistance - Influenza -
  • Resistance to entecavir (when a virus becomes insensitive to the antiviral) has been seen in lamivudine-refractory patients.
  • This happened without the use of antiviral agents, vaccines or radical measures having been taken in poultry farming, but thanks to the most effective means of disease defence called natural resistance.
  • Nonetheless, there is a potential risk of selection of HIV strains resistant to adefovir with possible cross-resistance to other antiviral medicinal products.
  • The pattern of amino acid substitutions in RT associated with resistance to efavirenz was independent of the other antiviral medications used in combination with efavirenz.
  • Tipranavir maintains significant antiviral activity (< 4-fold resistance) against the majority of HIV-1 clinical isolates showing post-treatment decreased susceptibility to the currently approved protease inhibitors: amprenavir, atazanavir, indinavir, lopinavir, ritonavir, nelfinavir and saquinavir.

Alternatives:

  • drug-resistant viruses
  • antimicrobial resistance
  • medication resistance in viruses
  • antiviral drug resistance
  • viral resistance to treatment

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