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pathogenesis vs disease development

Both 'pathogenesis' and 'disease development' are correct, but they are used in different contexts. 'Pathogenesis' is a term commonly used in medical and scientific fields to refer to the origin and development of a disease. 'Disease development' is a more general term that can be used in various contexts to describe the progression or evolution of a disease.

Last updated: March 25, 2024 • 843 views

This term is commonly used in medical and scientific fields to refer to the origin and development of a disease.

"pathogenesis"

The term 'pathogenesis' is used to describe the biological mechanisms by which a disease develops and progresses in an individual or population.
  • IL-6 has been implicated in the pathogenesis of diseases including inflammatory diseases, osteoporosis and neoplasia.
  • The CHMP also concluded that the potential role of tacrolimus in the pathogenesis of CTCL should be further investigated through mechanistic studies.
  • There is no consensus on the pathogenesis of these diseases, but early intervention in their progress is considered vital.
  • The complicated nature of these cases makes it impossible to determine what role, if any, rasagiline played in their pathogenesis.
  • The result is a reduction in intraocular pressure (IOP) which is a major risk factor in the pathogenesis of optic nerve damage and glaucomatous visual field loss.
  • With the knowledge of the pathogenesis and the within herd transmission, the results of diagnostic testing can better be understood.
  • New scientific information recently gathered by several Member States on bluetongue virus pathogenesis indicates that the trans-placental transmission of the bluetongue virus is likely to occur at least for serotype 8.
  • In the light of new scientific information recently gathered on bluetongue virus pathogenesis related to the possible trans-placental transmission of bluetongue, some precautionary measures should be taken to prevent the possible spread of the disease by pregnant animals or certain newborn animals.
  • Pathogenesis and improved diagnosis and control of avian influenza infections (Project Reference: QLK2-CT-2002-01454, Community funding: EUR 1,84 million).
  • Although the pathogenesis of ALS is not completely elucidated, it is suggested that glutamate (the primary excitatory neurotransmitter in the central nervous system) plays a role for cell death in the disease.
  • The projects tackle issues such as the development of tailored treatments for chronic heart failure, the impact of co-morbidity factors on the course of the disease and the pathogenesis of diastolic heart failure.
  • The Commission is aware of the importance of research focusing on controlling the activity of genes and gene products involved in cancer initiation and progression in order to have further insight into cancer pathogenesis and develop more effective therapies.
  • So angiogenesis is really a central process to the pathogenesis of cancer.
  • That landmark discovery paved the way for many important developments and diagnostics, and the treatment of HIV infections, and allowed us to understand more about the pathogenesis of HIV infections and its devastating consequences.
  • Constitutive activation of the PDGF receptor or the Abl protein tyrosine kinases as a consequence of fusion to diverse partner proteins or constitutive production of PDGF have been implicated in the pathogenesis of MDS/ MPD, HES/ CEL and DFSP.
  • Gastric acid is central in the pathogenesis of gastroduodenal ulcers and acid inhibition has been shown to effectively heal NSAID induced ulcers.
  • Taking into account the favourable evolution of the BSE epidemic and new data available from BSE pathogenesis studies, the European Commission submitted a new mandate to the European Food Safety Authority in October 2004 for an assessment of the age limit for the removal of SRM in bovines.
  • and evaluation of possible pathogenetic effects of GMO in man and animals
  • Childhood diseases are a field in which European cooperation is vital for the study of pathogenetic mechanisms underlying pediatric serious diseases as well as identification of new instruments for their prevention and therapy.
  • "traceability" processes, in particular relating to genetically modified organisms, including those based on recent biotechnology developments and evaluation of possible pathogenetic effects of GMO in man and animals;

Alternatives:

  • disease etiology
  • disease causation
  • disease mechanism

This term is a more general way to describe the progression or evolution of a disease and can be used in various contexts.

"disease development"

'Disease development' can be used to describe the overall process of how a disease evolves or progresses in a patient or within a population.
  • Discontinuation of VFEND should be considered if clinical signs and symptoms are consistent with liver disease development.
  • Autoimmune disease The development of auto-antibodies and autoimmune disorders has been reported during treatment with alpha interferons.
  • We have been able to follow the disease's development on maps as we have seen it spreading from one country to another.
  • Research on the brain and related diseases, human development and ageing.
  • If there was a social development disease, you wouldn't call it Asperger's, that's just me.
  • In this context, we must not forget that certain diseases hamper the development of the world's poorest countries.
  • These result in reduced immunity to disease and allow the development of tumours.
  • The intensive production of livestock confined to small areas facilitates the development of diseases which are treated by massive use of antibiotics.
  • Tackling new disease implies more costly development of drugs.
  • Poverty is a barrier to the development of a viable system of medical treatment, while at the same time the diseases prevent development and overcoming poverty.
  • identification of trends in the occurrence of pests and disease and development of fungi;
  • Moreover, in many respects there is a connection between animal health and welfare and the development of diseases that can be transferred to human beings.
  • The low relative humidity in summer prevents the development of diseases such as mildew, which are particularly harmful to the product.
  • Finally, the Council is particularly committed to combating another illness that is part of the group of neurodegenerative diseases, neurological development disorders and non-psychiatric brain diseases, namely Alzheimer's disease.
  • A horizontal approach is therefore taken at EU level, with the focus being on combating stigmatisation of and discrimination against people affected by neurodegenerative diseases, neurological development disorders and non-psychiatric brain diseases.
  • Research will aim both at the prevention of diseases and the development of effective treatments and medicines while ensuring equitable access to results of publicly funded research.
  • Research will aim both at optimising the prevention of diseases and the development of effective treatments and medicines while ensuring equitable access to the results of publicly-funded research.
  • The seventh Framework Programme includes collaborative activities on research into brain-related diseases, human development and ageing, with particular emphasis on how to turn basic discoveries into clinical applications.
  • The Seventh Framework Programme provides funding to a number of projects that address physical activity and its links to health promotion and disease prevention and development.
  • As per Annex 2.3 of the new Programme, activities related to rare diseases include the development of strategies and mechanisms for the exchange of information and prevention.

Alternatives:

  • progression of a disease
  • evolution of a disease
  • disease advancement

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