lyophilized vs freeze-dried

Both 'lyophilized' and 'freeze-dried' are correct terms used in the context of removing water from a substance by freezing it and then sublimating the frozen water under vacuum. They are interchangeable and commonly used in scientific and pharmaceutical fields.

Last updated: March 26, 2024 • 927 views

lyophilized

The term 'lyophilized' is correct and commonly used in scientific and pharmaceutical contexts to describe the process of freeze-drying.

It refers to the process of removing water from a substance by freezing it and then sublimating the frozen water under vacuum.

Examples:

The vaccine is lyophilized to increase its stability for storage and transportation.
The lyophilized powder can be reconstituted with water before use.

Show examples from the web [+]

IVEMEND is a lyophilized prodrug of aprepitant containing polysorbate 80 (PS80) for intravenous administration.
Inject all the solvent in the syringe into the vial of lyophilized vaccine and gently agitate to mix thoroughly.
The inorganic, lyophilized form of arsenic trioxide, when placed into solution, immediately forms the hydrolysis product arsenious acid (AsIII).
In three comparative controlled trials, the immune response elicited by Rotarix liquid formulation was comparable to the one elicited by Rotarix lyophilized formulation.
Advate is to be administered intravenously after reconstitution of the lyophilized product with the provided sterilised water for injections.
Reconstitution instructions To reconstitute the vaccine, inject all the solvent in the syringe into the vial of lyophilized vaccine and gently agitate to mix thoroughly.
Powder for concentrate for solution for infusion White to off-white lyophilized cake or powder
The EEC standard for bovine PPD has a potency of 50000 Community tuberculin units (CTU) per mg of PPD and is dispensed lyophilized in ampoules containing 1,8 mg of PPD, i.e. 0,00002 mg PPD has a potency equal to one Community tuberculin unit.
Appearance of the powder: white lyophilized pellet Appearance of the solvent: clear colourless solution
Lyophilized vials containing a reconstituted dose of 25 mg/ ml are available from which doses less than 25 mg can be administered.
Add the water for injections by slow drop-wise addition down the side of the vial and not directly onto the lyophilized cake.
lyophilized PPD tuberculins: eight years;
8 wise addition of the water for injection down the inside of the vial and not directly onto the lyophilized cake.
This is done by slow drop- wise addition of the water for injection down the inside of the vial and not directly onto the lyophilized cake.
In addition to its content in international agglutinating units, 1 ml of this lyophilized bovine serum must contain 1000 sensitizing units which fix the complement.
ADVATE is to be administered intravenously after reconstitution of the lyophilized product with the provided sterilised water for injections.
Powder for concentrate for solution for infusion White to off-white lyophilized cake or powder

Alternatives:

freeze-dried
cryodesiccated
sublimated
dried under vacuum

freeze-dried

The term 'freeze-dried' is correct and commonly used in scientific and pharmaceutical contexts to describe the process of lyophilization.