lyophilized vs freeze-dried

Both 'lyophilized' and 'freeze-dried' are correct terms used in the context of removing water from a substance by freezing it and then sublimating the frozen water under vacuum. They are interchangeable and commonly used in scientific and pharmaceutical fields.

Last updated: March 26, 2024 • 1071 views

The term 'lyophilized' is correct and commonly used in scientific and pharmaceutical contexts to describe the process of freeze-drying.

"lyophilized"

It refers to the process of removing water from a substance by freezing it and then sublimating the frozen water under vacuum.

Examples:

The vaccine is lyophilized to increase its stability for storage and transportation.
The lyophilized powder can be reconstituted with water before use.

Show examples from the web [+]

IVEMEND is a lyophilized prodrug of aprepitant containing polysorbate 80 (PS80) for intravenous administration.
Inject all the solvent in the syringe into the vial of lyophilized vaccine and gently agitate to mix thoroughly.
The inorganic, lyophilized form of arsenic trioxide, when placed into solution, immediately forms the hydrolysis product arsenious acid (AsIII).
In three comparative controlled trials, the immune response elicited by Rotarix liquid formulation was comparable to the one elicited by Rotarix lyophilized formulation.
Advate is to be administered intravenously after reconstitution of the lyophilized product with the provided sterilised water for injections.
Reconstitution instructions To reconstitute the vaccine, inject all the solvent in the syringe into the vial of lyophilized vaccine and gently agitate to mix thoroughly.
Powder for concentrate for solution for infusion White to off-white lyophilized cake or powder
The EEC standard for bovine PPD has a potency of 50000 Community tuberculin units (CTU) per mg of PPD and is dispensed lyophilized in ampoules containing 1,8 mg of PPD, i.e. 0,00002 mg PPD has a potency equal to one Community tuberculin unit.
Appearance of the powder: white lyophilized pellet Appearance of the solvent: clear colourless solution
Lyophilized vials containing a reconstituted dose of 25 mg/ ml are available from which doses less than 25 mg can be administered.
Add the water for injections by slow drop-wise addition down the side of the vial and not directly onto the lyophilized cake.
lyophilized PPD tuberculins: eight years;
8 wise addition of the water for injection down the inside of the vial and not directly onto the lyophilized cake.
This is done by slow drop- wise addition of the water for injection down the inside of the vial and not directly onto the lyophilized cake.
In addition to its content in international agglutinating units, 1 ml of this lyophilized bovine serum must contain 1000 sensitizing units which fix the complement.
ADVATE is to be administered intravenously after reconstitution of the lyophilized product with the provided sterilised water for injections.
Powder for concentrate for solution for infusion White to off-white lyophilized cake or powder

Alternatives:

freeze-dried
cryodesiccated
sublimated
dried under vacuum

The term 'freeze-dried' is correct and commonly used in scientific and pharmaceutical contexts to describe the process of lyophilization.

"freeze-dried"

It refers to the process of removing water from a substance by freezing it and then sublimating the frozen water under vacuum.

Examples:

The freeze-dried coffee retains its flavor and aroma.
The freeze-dried fruit is lightweight and easy to transport.

Show examples from the web [+]

Reteplase is supplied as a freeze-dried substance in vials.
Aseptically reconstitute the freeze-dried vaccine with 0.3 ml of the sterile solvent provided.
Preparation of NeoRecormon Multidose solution (1) Take the vial with the freeze-dried substance out of the package.
The freeze-dried fraction must be reconstituted with 1 ml of the specific diluent to obtain a solution containing 5 MU of recombinant interferon.
the nature and quantity of the reconstituting liquid for the freeze-dried preparation.
Except where the context otherwise requires, throughout the nomenclature any reference to 'dried' products also covers products which have been dehydrated, evaporated or freeze-dried.
Aseptically reconstitute the freeze-dried vaccine with 0.3 ml of the sterile solvent provided.
Piñatas and tacos and freeze-dried ice cream.
Every foodstuff on board is either frozen, freeze-dried, canned or packaged.
The final product shall be freeze-dried.
Master stocks of the organism are stored as freeze-dried ampoules.
Monoclonal antibody: 3-17-A3 (supplied as hybridoma tissue-culture supernatant) directed against the group-specific polypeptide VP7, stored at -20 ºC or freeze-dried and diluted 1/100 with blocking buffer before use.
We haven't asked ourselves, why freeze-dried?
Every day Stephen eats the same meal - a freeze-dried vegetarian lasagne, hermetically sealed for maximum life expectancy.
This also applies to human blood, regardless of its state (liquid, solid, frozen, freeze-dried etc.).
During preparation no antiseptic or bacteriostatic substance shall be added. The final product shall be freeze-dried.
When dissolving more than one sphere, it should be checked visually whether all freeze-dried material has dissolved completely before the solution is transferred to the next ampoule to be reconstituted.
What INVANZ looks like and contents of the pack INVANZ is a sterile, white to off-white, freeze-dried powder.
Since the stability of IBV in suspension may be low due to sensitivity to high temperatures and impurities, water used for dissolving the freeze-dried vaccine should be cool and of good quality.
The freeze-dried fraction must be reconstituted with 1 ml of the specific diluent to obtain, depending on the presentation, a suspension containing 5 MU or 10 MU of recombinant interferon.

Alternatives:

lyophilized
cryodesiccated
sublimated
dried under vacuum

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lyophilized vs freeze-dried

"lyophilized"

"freeze-dried"

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