It would be of your disadvantage. vs It would be in your disadvantage.

Some examples from the web:

• It's remarkable, Spock, you made so many despite your disadvantage.
• These elements are to your disadvantage.
• It would, for example, be considered an abuse to sell at excessive prices or to give discriminatory advantages to certain customers, thereby putting competitors at a disadvantage.
• This is particularly important in communities facing multiple disadvantages.
• But the advantage outweighs the disadvantage.
• Employment is especially important in overcoming area-based disadvantage.
• But decoupling direct payments can also have its disadvantages.
• The common problems are those of remoteness and transport disadvantage.
• Most methods of removing flesh have disadvantages.
• All writing systems have advantages and disadvantages.
• Surely Pompey had Caesar at greater disadvantage.
• Emissions trading also has many disadvantages.
• He never saw his wheelchair as a disadvantage.
• This puts European manufacturers at a competitive disadvantage.
• Having said that, I do not believe a wholly public system is even conceivable, as it would end up further stifling the drive for efficiency caused by having competitors, to the consumers' disadvantage.
• You know, it put me at a big disadvantage.
• In our case, it's a disadvantage.
• But it's too big a disadvantage.
• No other Member State is at such a disadvantage.
• Obviously the traditional sour milk cheeses are therefore at a disadvantage.

Some examples from the web:

• It's remarkable, Spock, you made so many despite your disadvantage.
• These elements are to your disadvantage.
• It would, for example, be considered an abuse to sell at excessive prices or to give discriminatory advantages to certain customers, thereby putting competitors at a disadvantage.
• This is particularly important in communities facing multiple disadvantages.
• But the advantage outweighs the disadvantage.
• Employment is especially important in overcoming area-based disadvantage.
• But decoupling direct payments can also have its disadvantages.
• The common problems are those of remoteness and transport disadvantage.
• Most methods of removing flesh have disadvantages.
• All writing systems have advantages and disadvantages.
• Surely Pompey had Caesar at greater disadvantage.
• Emissions trading also has many disadvantages.
• He never saw his wheelchair as a disadvantage.
• This puts European manufacturers at a competitive disadvantage.
• Having said that, I do not believe a wholly public system is even conceivable, as it would end up further stifling the drive for efficiency caused by having competitors, to the consumers' disadvantage.
• You know, it put me at a big disadvantage.
• In our case, it's a disadvantage.
• But it's too big a disadvantage.
• No other Member State is at such a disadvantage.
• Obviously the traditional sour milk cheeses are therefore at a disadvantage.