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in an ATP dependent manner vs with an ATP dependent manner

The correct phrase is 'in an ATP-dependent manner.' The preposition 'in' is commonly used to describe the way in which an action is performed, followed by the adjective 'ATP-dependent' to specify the manner. 'With' is not the appropriate preposition in this context.

Last updated: March 24, 2024 • 1002 views

in an ATP dependent manner

This phrase is correct and commonly used in scientific contexts to describe processes that rely on ATP for energy.

This phrase is used to indicate that a certain process or action is dependent on ATP for its execution.

Examples:

  • The enzyme catalyzes the reaction in an ATP-dependent manner.
  • Protein synthesis occurs in an ATP-dependent manner.
  • Cell division is regulated in an ATP-dependent manner.
  • The transport of ions across the cell membrane is carried out in an ATP-dependent manner.
  • Muscle contraction is driven in an ATP-dependent manner.
  • Sulphonylureas regulate insulin secretion by closing the ATP-dependent potassium channels in the beta cell membrane.
  • Nateglinide closes ATP-dependent potassium channels in the beta-cell membrane with characteristics that distinguish it from other sulphonylurea receptor ligands.
  • Repaglinide closes ATP-dependent potassium channels in the β -cell membrane via a target protein different from other secretagogues.
  • Enalapril administration once daily lowered trough blood pressure in a dose-dependent manner.
  • 20 hours of practical MCC training, or 15 hours in the case of student pilots attending an ATP integrated course.
  • 20 hours of practical MCC training or 15 hours, in the case of student pilots attending an ATP(H)/IR integrated course.
  • In an oral high-dose tolerability study in angina patients, the incidence of dizziness, nausea, and vomiting increased in a dose-dependent manner.
  • At the end of three weeks, losartan administration once daily lowered trough blood pressure in a dose- dependent manner.
  • At the end of three weeks, losartan administration once daily lowered trough blood pressure in a dose-dependent manner.
  • In clinical studies, serum free IgE levels were reduced in a dose-dependent manner within one hour following the first dose and maintained between doses.
  • QT prolongation Tasigna has been shown to prolong cardiac ventricular repolarisation as measured by the QT interval on the surface ECG in a concentration-dependent manner.
  • Plasma GL-3 was cleared in a dose dependent manner, but was less consistent at the dose of 0.3 mg/ kg.
  • At the 4 cidofovir levels (12.5 to 100 µg/ ml) tested, the percentage of damaged metaphases and number of aberrations per cell increased in a concentration-dependent manner.
  • By enhancing active incretin levels, sitagliptin increases insulin release and decreases glucagon levels in a glucose- dependent manner.
  • Increases in ATP content in the lymph nodes are measured by the luciferin/luciferase method using an ATP measurement kit, which measures bioluminescence in Relative Luminescence Units (RLU).
  • Adults with growth hormone deficiency show low bone mineral density and in the childhood-onset patient, NutropinAq has been shown to increase spine bone mineral density in a dose-dependent manner.
  • Eptifibatide inhibits platelet aggregation in a dose- and concentration-dependent manner as demonstrated by ex vivo platelet aggregation using adenosine diphosphate (ADP) and other agonists to induce platelet aggregation.
  • Applicants who have completed an ATP(H)/IR, ATP(H), CPL(H)/IR or CPL(H) integrated training course shall be exempted from the requirement in (b).
  • in the case of applicants who have not completed an ATP(H)/IR, ATP(H), or CPL(H)/IR integrated training course, have completed at least 70 hours as PIC on helicopters.

Alternatives:

  • in a manner dependent on ATP
  • using ATP as a dependency
  • relying on ATP for its execution
  • through an ATP-dependent process
  • via an ATP-dependent mechanism

with an ATP dependent manner

This phrase is incorrect. 'With' is not the appropriate preposition to convey the relationship between the action and its dependence on ATP.

  • Sulphonylureas regulate insulin secretion by closing the ATP-dependent potassium channels in the beta cell membrane.
  • Nateglinide closes ATP-dependent potassium channels in the beta-cell membrane with characteristics that distinguish it from other sulphonylurea receptor ligands.
  • Repaglinide closes ATP-dependent potassium channels in the β -cell membrane via a target protein different from other secretagogues.
  • Enalapril administration once daily lowered trough blood pressure in a dose-dependent manner.
  • 20 hours of practical MCC training, or 15 hours in the case of student pilots attending an ATP integrated course.
  • 20 hours of practical MCC training or 15 hours, in the case of student pilots attending an ATP(H)/IR integrated course.
  • In an oral high-dose tolerability study in angina patients, the incidence of dizziness, nausea, and vomiting increased in a dose-dependent manner.
  • At the end of three weeks, losartan administration once daily lowered trough blood pressure in a dose- dependent manner.
  • At the end of three weeks, losartan administration once daily lowered trough blood pressure in a dose-dependent manner.
  • In clinical studies, serum free IgE levels were reduced in a dose-dependent manner within one hour following the first dose and maintained between doses.
  • QT prolongation Tasigna has been shown to prolong cardiac ventricular repolarisation as measured by the QT interval on the surface ECG in a concentration-dependent manner.
  • Plasma GL-3 was cleared in a dose dependent manner, but was less consistent at the dose of 0.3 mg/ kg.
  • At the 4 cidofovir levels (12.5 to 100 µg/ ml) tested, the percentage of damaged metaphases and number of aberrations per cell increased in a concentration-dependent manner.
  • By enhancing active incretin levels, sitagliptin increases insulin release and decreases glucagon levels in a glucose- dependent manner.
  • Increases in ATP content in the lymph nodes are measured by the luciferin/luciferase method using an ATP measurement kit, which measures bioluminescence in Relative Luminescence Units (RLU).
  • Adults with growth hormone deficiency show low bone mineral density and in the childhood-onset patient, NutropinAq has been shown to increase spine bone mineral density in a dose-dependent manner.
  • Eptifibatide inhibits platelet aggregation in a dose- and concentration-dependent manner as demonstrated by ex vivo platelet aggregation using adenosine diphosphate (ADP) and other agonists to induce platelet aggregation.
  • Applicants who have completed an ATP(H)/IR, ATP(H), CPL(H)/IR or CPL(H) integrated training course shall be exempted from the requirement in (b).
  • in the case of applicants who have not completed an ATP(H)/IR, ATP(H), or CPL(H)/IR integrated training course, have completed at least 70 hours as PIC on helicopters.

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