had a significate effect vs had a significative effect

Some examples from the web:

• The effect was significant from the first year.
• No significant effect on didanosine and etravirine PK parameters is seen.
• However, no significant effect on fracture rates was demonstrated.
• The Commission also mentioned that the term significant effect in Article 6 of the Habitats Directive had a broader meaning than irreversible effect.
• The effect of any changes in actuarial assumptions that have had a significant effect on the actuarial present value of promised retirement benefits shall also be disclosed.
• In an interaction study based on data from 17 patients, assessing the effect of omeprazole, a potent CYP2C19 inhibitor, there was no significant effect on the pharmacokinetics of bortezomib.
• When a solubilising agent is used it must have no significant effect on survival nor visible adverse effect on the early-life stages as revealed by a solvent-only control.
• The illumination is only an additional effect enhancing the decorative effect.
• However, despite a possible effect on plasma levels, these interactions have not demonstrated clinical significance.
• A significant weather advisory is now in effect.
• A name can have a significant effect upon a person's sense of identity.
• Subdural hematoma with significant mass effect.
• This kind of head trauma can have a significant effect on brain function.
• Sounds as if the doctor's visit had a significant effect.
• So these are small actions that can amount to a significant effect to improve local environmental health.
• ...didn't seem to be significant enough to have any major effect.
• Therefore the additional effect of the Working Time Directive is not significant for road safety.
• Lamotrigine may induce its own metabolism but the effect is modest and unlikely to have significant clinical consequences.
• There was no clinically significant effect of lamotrigine on QT interval compared to placebo.
• These metabolites have no significant effect on acid secretion.

Some examples from the web:

• In relation with the development of the new tapster to which the Honourable Member refers, the Commission takes good note that the new process used should allow a significative reduction of CO 2 emissions by 31 %.