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a marked effect was observed vs more pronounced effect was observed

Both phrases are correct, but they are used in slightly different contexts. 'A marked effect was observed' is a common phrase used to indicate that a noticeable or significant effect was noticed. On the other hand, 'a more pronounced effect was observed' implies that the effect was not only noticeable but also stronger or more distinct compared to something else.

Last updated: March 24, 2024 • 778 views

a marked effect was observed

This phrase is correct and commonly used in English.

This phrase is used to indicate that a noticeable or significant effect was noticed.
  • This cohesive approach has also had a marked effect on other Member State policies.
  • The surprising unanimity of these demonstrations has had a marked effect on French public opinion.
  • In animal reproductive studies, no teratogenic effect was observed.
  • You change that system, and you could have a marked effect on the cancer.
  • However, as expected for a compound which is cleared almost exclusively via the kidneys, renal function has a marked effect on the kinetics of hydrochlorothiazide.
  • The additional wind resistance from the fitting of a high roof van body has a marked effect on the fuel efficiency of a vehicle.
  • This latter clinical effect was observed after more than one year of treatment.
  • Similar food effect was observed for Rasilez HCT as for the individual monotherapies.
  • Full treatment effect was observed between 2 and 8 weeks.
  • This lack of pharmacodynamic effect was observed with a sub-therapeutic dose of repaglinide.
  • Similarly a larger treatment effect was observed in those patients with visual hallucinations (see Table 6).
  • A more pronounced glucose-lowering effect was observed in obese patients.
  • A marked improvement in the CD4+ cell percent was observed through week 48 for both dose groups.
  • No significant local irritant effect was observed when the rapidly-dissolving form was tested in a hamster cheek pouch mucous membrane irritation assay.
  • The no-observed-effect-level for developmental effects was observed at 3- (valsartan) and 4- (amlodipine) fold the clinical exposure (based on AUC).
  • Antiemetic effect An antiemetic effect was observed in preclinical studies with paliperidone.
  • 85 to 90% of the maximal blood- pressure-lowering effect was observed after 2 weeks.
  • Similarly a larger effect was observed in Parkinson's disease patients with visual hallucinations (see section 5.1).
  • No evidence of direct foetal toxicity or teratogenic effects was observed for ibandronic acid in intravenously or orally treated rats and rabbits.
  • In healthy volunteers, a marked dose-related decrease in plasma uric acid levels was observed across the dose range 0.05 mg/ kg to 0.20 mg/ kg of Fasturtec.

Alternatives:

  • a noticeable effect was observed
  • a significant effect was observed

more pronounced effect was observed

This phrase is correct and commonly used in English.

This phrase implies that the effect was not only noticeable but also stronger or more distinct compared to something else.
  • A more pronounced glucose-lowering effect was observed in obese patients.
  • A more pronounced effect at 400 mg BID therefore cannot be excluded.
  • 60 mirtazapine a more pronounced effect can not be excluded, it is advisable to monitor the INR in case of concomitant treatment of warfarin with mirtazapine.
  • A more pronounced transient increase of liver enzymes without clinical symptoms was observed in the 5-ALA HCl- treated patients.
  • In animal reproductive studies, no teratogenic effect was observed.
  • As at a higher dose of mirtazapine a more pronounced effect can not be excluded, it is advisable to monitor the INR in case of concomitant treatment of warfarin with mirtazapine.
  • This latter clinical effect was observed after more than one year of treatment.
  • Similar food effect was observed for Rasilez HCT as for the individual monotherapies.
  • Full treatment effect was observed between 2 and 8 weeks.
  • This lack of pharmacodynamic effect was observed with a sub-therapeutic dose of repaglinide.
  • Similarly a larger treatment effect was observed in those patients with visual hallucinations (see Table 6).
  • No significant local irritant effect was observed when the rapidly-dissolving form was tested in a hamster cheek pouch mucous membrane irritation assay.
  • The no-observed-effect-level for developmental effects was observed at 3- (valsartan) and 4- (amlodipine) fold the clinical exposure (based on AUC).
  • Antiemetic effect An antiemetic effect was observed in preclinical studies with paliperidone.
  • 85 to 90% of the maximal blood- pressure-lowering effect was observed after 2 weeks.
  • Similarly a larger effect was observed in Parkinson's disease patients with visual hallucinations (see section 5.1).
  • No evidence of direct foetal toxicity or teratogenic effects was observed for ibandronic acid in intravenously or orally treated rats and rabbits.
  • A subgroup analysis showed that no treatment effect was observed as compared to placebo on the 6-minute walk test in the subgroup of patients with secondary pulmonary hypertension.
  • During standard fertility studies, impairment of fertility was observed in female mice receiving capecitabine; however, this effect was reversible after a drug-free period.
  • No effect was observed on the fertility of male and female rats or gestation in rats.

Alternatives:

  • a stronger effect was observed
  • a clearer effect was observed

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